Lisa S. Poritz, MD, FACS, FASCRS

Lisa S. Poritz, MD, FACS, FASCRS Dr. Poritz received her medical degree from Northwestern University School of Medicine and then completed a research fellowship and general residency at The Milton S. Hershey Medical Center, Pennsylvania State University College of Medicine.  She then completed a colon and rectal residency at the University of Toronto and has been in practice since 2000.  Prior to joining the practice at Colorectal Health Northwest, Dr. Poritz was an Associate Professor of Colon and Rectal Surgery at the Milton S. Hershey Medical Center.  She brings to the practice extensive experience in the surgical management of inflammatory bowel disease, while providing treatment for the full spectrum of colorectal disease.  Dr. Poritz is board certified by both the American Board of Surgery and the American Board of Colon and Rectal Surgery, and is a fellow of the ACS and the ASCRS.

EDUCATION

Undergraduate:
Lafayette College, Easton PA
August 1984-May 1988
Major: Biology/Chemistry

Medical School:
Northwestern University Feinberg School of Medicine, Chicago IL
August 1988-June 1992

General Surgery Residency:
Department of Surgery
The Pennsylvania State University College of Medicine, The Milton S. Hershey Medical Center, Hershey, PA
Internship: July 1992-June 1993
Residency: July 1993-June 1995
Surgical Research Fellowship: July 1995-June 1997
Residency: July 1997-June 1998
Chief Resident: July 1998-June 1999

Colon and Rectal Residency:
University of Toronto Hospitals
Division of Colon and Rectal Surgery
Toronto, Ontario, Canada
July 1999-June 2000

BOARD CERTIFICATION

American Board of Surgery:
Initial certification: September 11, 2001
Recertification: November 2011

American Board of Colon and Rectal Surgery:
Initial certification: September 29, 2001
Recertification: January 2012

Previous Academic Appointments:
The Pennsylvania State University, The Milton S. Hershey Medical Center
Associate Professor, Department of Surgery and Department of Cellular & Molecular Physiology
Hershey, PA
May 2009 – August 2016

The Pennsylvania State University, The Milton S. Hershey Medical Center
Associate Professor, Department of Surgery
Hershey, PA
July 2006 – May 2009

The Pennsylvania State University, The Milton S. Hershey Medical Center
Assistant Professor, Department of Surgery
Hershey, PA
July 2000-July 2006

Teaching and Advising Activities

The Pennsylvania State University The Milton S. Hershey Medical Center
Program Director of Colon and Rectal Residency
Department of Surgery
July 1, 2006 – July 1, 2014

“Colon Cancer” Core Surgery Lectures to Third Year Medical Students – 2005 - 2008
“Bowel Obstruction” Core Surgery Lectures to Third Year Medical Students – 2000 - 2004 Colorectal Surgery Conference – every week.

“Small Bowel” - Basic and Clinical Science Series to Surgery Residents – 3 times every 2 years
– 2000 – 2002

Surgical Presentation to GI Medicine Conference – once a month – 2000 - 2006
Assistant Facilitator Guide Director, GI PBL Course to Second Year Medical Students – Fall
Semester 2002 - 2004

Programs Directed:

Colorectal Cancer Symposium – Advances in the Management of Colorectal Cancer
The Pennsylvania State University, The Milton S. Hershey Medical Center
Hershey, Pennsylvania
March 15, 2008

Colorectal Cancer Symposium – Advances in the Management Of Colorectal Cancer: What You Need to Know to Take Care of Your Patients in 2005
The Pennsylvania State University, The Milton S. Hershey Medical Center
Hershey, Pennsylvania
March 19, 2005

EXTERNAL COMMITTEES

  • American Society of Colon and Rectal Surgeons
    • Member, Research Committee, 2002-2013
    • Member, Program Committee, 2002 – 2005, 2007 - 2010
    • Member, Young Investigators Committee, 2002 - 2013
    • Member, Awards Committee, 2003-2006
    • Research Foundation Trustee, 2008- 2013
  • The Association for Academic Surgery
    • Member, Educational Committee, 2004 – 2007
    • Member, Membership Committee, 2007 – 2009
    • Councilor, Executive Council, 2010 - 2012
    • Nominating Committee, 2011 – 2012
  • Hershey Endoscopy Center
    • Treasurer, 2003 – 2015

Editorial Activities:
Associate Editor: Diseases of the Colon and Rectum, 2008 – 2014
Guest Editor: Seminars in Colon and Rectal Surgery: “Update in IBD” Volume 17, Number 2 (June 2006)
Editorial Board: World Journal of Gastroenterology, 2010 – 2011
Reviewer: Diseases of the Colon and Rectum, 2002-present

ORGANIZATIONS

  • American College of Surgeons, 1995
    • Fellow, 2003
  • Association for Academic Surgery, 1996
    • Active Member, 2001
    • Senior Member, 2012
  • American Society of Colon & Rectal Surgeons
    • 1998, Member, 2001, Fellow 2004
  • The Society for Surgery of the Alimentary
    • Tract, Candidate Group, 1997 – 2004
    • Active Member - Present
  • Association of Women Surgeons, 1992 - 2011
  • Inflammation Research Association, 1996
  • Hershey Surgical Society, 1999
  • Central Surgical Association, 2003
  • American Physiological Society, 2005
  • Association of Program Directors for Colon & Rectal Surgery, 2006
  • Society of University Surgeons, 2007
  • Oregon Medical Society, 2016

AWARDS AND HONORS

The Victor W. Fazio, MB, MS Award for Editorial Excellence in Recognition of Outstanding Work on Behalf of Diseases of the Colon & Rectum American Society of Colon and Rectal Surgeons, June 2012, Robert D. Madoff, M.D., Editor-in-Chief and Steven D. Wexner, M.D., President

Harry E. Bacon Foundation Award for paper at the American Society of Colon and Rectal Surgeons Meeting, Vancouver, BC, Canada, May 2011; “Mutations in IRGM are Associated with More Frequent Need for Surgery in Ileocolonic Crohn’s Disease Patients.” Sehgal, R., Berg, A., Hegarty, J.P., Lin, Z., Poritz, L.S. and Koltun W.A.

The Howard E. Morgan Award for Outstanding Achievement in Basic Science Research Awarded by the Department of Cellular and Molecular Physiology, The Pennsylvania State University,
The Milton S. Hershey Medical Center: Wisner, Doug and Poritz, L.S. (Mentor)

Harry E. Bacon Foundation Award for paper at the American Society of Colon and Rectal Surgeons Meeting, Philadelphia, Pennsylvania, May 2005; “Increased Presence of NOD2 Mutations in PatientsUndergoing Ileocolectomy for Crohn’s Disease.” Poritz, L.S., Zhang, W.J., Thompson, J., Boyer, M.,Galka, E., and Koltun W.A.

Harry E. Bacon Foundation Award for paper at the American Society of Colon and Rectal Surgeons Meeting, Philadelphia, Pennsylvania, June 1997; “Bowel Permeability is Improved in Crohn’s Disease After Ileocolectomy.” Koltun, W.A., Tilberg, A.F., Page, M.J., and Poritz, L.S.

2nd prize for basic science research, Central PA Chapter of the ACS Surgeons Residents Competition, Hershey, Pennsylvania, April 11, 1997, “Expression of the Tight Junction Protein ZO-1 in an Animal Model of Intestinal Inflammation and Increased Permeability.” Poritz, L.S., Lynch, C.J., Khin, S., Tilberg, A.F., Page, M.J., and Koltun, W.A.

Bristol-Myers Squibb Scholar in Surgery Award, 1997

Winner of the Building Industry Association of Lancaster County Award for Cancer Research,
Hershey, Pennsylvania, November, 1996

Winner of the Finkelstein Memorial Symposium, Hershey Medical Center, Hershey, Pennsylvania, May 11, 1996, “Lymphocyte Function Associated Antigen-1 and Graft Versus Host Disease.”

PEER REVIEWED ARTICLES

  1. Sharma, P., Page, M., Poritz, L., Koltun, W., and Chorney, M.J.: An Increased T Cell Population in the Intestine of Thymus-Leukemia Antigen Transgenic Mice. Cellular Immunology, 176:153-157, 1997.
  2. Poritz, L.S., Tilberg, A, and Koltun, W.A.: Decreased Expression of Lymphocyte Function Associated Antigen-1 (LFA-1) on Peripheral Blood Lymphocytes (PBLs) in Graft Versus Host Disease (GVHD). Journal of Surgical Research, 69(2):316-320, 1997.
  3. Poritz, L.S., Page, M.J., Tilberg, A.F., and Koltun, W.A.: Tumor Necrosis Factor Binding Protein (TNFbp) Treatment Improves Graft Versus Host Disease (GVHD) After Small Bowel Transplantation. Surgical Forum, 48:495-497, 1997.
  4. Page, M.J., Poritz, L.S., Sheaffer, N., Ten Elshof, A., Tilberg, A., Chorney, M.J., and Koltun, W.A.: CD1d Expression is Associated with the CD4+ and+ Intraepithelial Lymphocyte Subset in Normal Humans and Those with Crohn’s Disease and Ulcerative Colitis. Surgical Forum, 48:206-209, 1997.
  5. Poritz, L.S., Olt, G., Ruggerio, F., Tilberg, A., Colony, P.C., and Koltun, W.A.: Increased LFA-1 Expression in the Intestines of Rats with GVHD After Small Bowel Transplantation. Digestive Diseases and Sciences, 43(2):221-228, 1998.
  6. Poritz, L.S., Page M.J., Tilberg, A.F., Olt, G., Ruggiero F., and Koltun, W.A.: Monoclonal Antibody (MoAb) to Lymphocyte Function Associated Antigen-1 (LFA- 1) Improves Graft Versus Host Disease (GVHD). Diseases of the Colon and Rectum, 41(3):299-309, 1998.
  7. Page M.J., Dreese, J.A., Poritz, L.S., and Koltun, W.A.: Cytomegalovirus (CMV) Enteritis: A Highly Lethal Condition Requiring Early Detection and Intervention. Diseases of the Colon and Rectum, 41(5):619-623, 1998.
  8. Koltun, W.A., Tilberg, A.F., Page, M.J., and Poritz, L.S.: Bowel Permeability is Improved in Crohn’s Disease After Ileocolectomy. Diseases of the Colon and Rectum, 41(6):687-690, 1998.
  9. Poritz, L.S., Page, M.J., Tilberg, A.F., and Koltun, W.A.: Amelioration of Graft Versus Host Disease with Anti-ICAM-1 Therapy. Journal of Surgical Research, 80:280-286, 1998.
  10. Page, M.J, Poritz, L.S., Tilberg, A.F., Zhang, W.J., Chorney, M.J., and Koltun, W.A.: CD1d-Restricted Cellular Lysis by a Novel Subset of Peripheral Blood Lymphocytes: Relevance to the Inflammatory Bowel Diseases. Journal of Surgical Research. 92:214-221, 2000.
  11. Poritz, L.S., Blackstein, M., Berk, T., Gallinger, S., McLeod, R., and Cohen, Z.: Extended Follow-up of Patients Treated with Cytotoxic Chemotherapy (CCT) for Intraabdominal Desmoid Tumors (DTs): Diseases of the Colon and Rectum, 44:1268-1273, 2001.
  12. Poritz, L.S., Rowe, W., Koltun, W.: Remicade Does Not Abolish the Need for Surgery in Fistulizing Crohn’s Disease. Diseases of the Colon and Rectum, 45:771-775, 2002.
  13. Page, M.J., Poritz, L.S., Kunselman, M.A., Koltun, W.A.: Factors Affecting Surgical Risk in Elderly Patients with Inflammatory Bowel Disease. Journal of Gastrointestinal Surgery, 6(4):606-613, 2002.
  14. Evans, J., Poritz, L.S., and MacRae, H.: Influence of Experience on Laparoscopic Ileocolic Resection for Crohn’s Disease. Diseases of the Colon and Rectum, 45(12):1595-1600, 2002.
  15. Poritz, L.S., Koltun WA: Surgical Management of Ulcerative Colitis in the Presence of Primary Sclerosing Cholangitis. Diseases of the Colon and Rectum, 46(2):173-178, 2003.
  16. Poritz, L.S., Garver, K., Tilberg, A.F., Koltun, W.A.: Tumor Necrosis Factor Alpha Disrupts Tight Junction Assembly. The Journal of Surgical Research, 116:14-18, 2004.
  17. Zhang, W.J., Koltun, W.A., Thompson, J.L., Tilberg, A.F., Galka, E., Poritz, L.S., and Chorney, M.J.: Human B. Lymphoblast Cell Lines Defective of Stat6 Signaling Produce High Levels of Proinflammatory Cytokines IL-12, TNF and IFN. International Journal Of Oncology, 24: 447-453, 2004.
  18. Galka, E., Thompson, J., Zhang, W., Poritz, L., Koltun, W.: STAT6 Null Phenotype Human Lymphocytes Exhibit Increased Apoptosis. Journal of Surgical Research, 122:14- 20, 2004.
  19. Poritz, L.S., Gagliano, A., McLeod, R., MacRae, H., Cohen, Z.: Surgical Management of Cutaneous Abdominal Fistulas in Crohn’s Disease – A 17 Year Experience. International Journal of Colon and Rectal Surgery, 19:481-485, 2004.
  20. Swenson, BR., Hollenbeak, CS., Poritz, LS., and Koltun, WA: Modified Two-Stage Ileal Pouch Anal Anastomosis: Equivalent Outcomes with Less Resource Utilization. Diseases
    of the Colon and Rectum, 48(2): 256-261, 2005.
  21. Poritz, L.S., Rowe, W.A., Swenson, B., Hollenbeak, C., Koltun, W: Intravenous Cyclosporine (CYA) for the Treatment of Severe Steroid Refractory Ulcerative Colitis (UC): What is the Cost? Diseases of the Colon and Rectum, 48(9):1685-1690, 2005.
  22. Poritz, L.S.: How Should Complex Crohn’s Disease be Treated in the Remicade Era? Journal of Gastrointestinal Surgery, 10(5):633-4, May 2006.
  23. Fitzpatrick, L.R., Small, J.S., Poritz, L.S., McKenna, K.J. and Koltun, W.A.: Enhanced Intestinal Expression of the Proteasome Subunit Low Molecular Mass Polypeptide 2 (LMP2) in Patients with Inflammatory Bowel Disease. Diseases of the Colon & Rectum, 50(3):337-350, 2007.
  24. Poritz, L.S., Koltun, W.A.: Percutaneous Drainage and Ileocolectomy for Spontaneous Intraabdominal Abscess in Crohn’s Disease. Journal of Gastrointestinal Surgery, 11(2):204-
    208, 2007.
  25. Poritz, L.S., Garver, K.I., Green, C., Fitzpatrick, L., Ruggiero, F., and Koltun, W.A.: Loss of The Tight Junction Protein ZO-1 in Dextran Sulfate Sodium Induced Colitis. Journal of Surgical Research, 140:12-19, 2007.
  26. Wisner, D, Green, C., and Poritz, L.S.: Opposing Regulation of the Tight Junction Protein Claudin-2 by Interferon-γ and Interleukin-4. Journal of Surgical Research, 144:1-7, 2008.
  27. Poritz, L.S., Lebo, M.A., Bobb, A.D., Ardell, C.M. and Koltun, W.A.: Management of Peristomal Pyoderma Gangrenosum. Journal American College of Surgeons, 206:311-5, 2008.
  28. Pastor, D.M., Pauli, E.M., Koltun, W.A., Haluck, R.S., Shope, T.R. and Poritz, L.S.: Parastomal Hernia Repair: A Single Center Experience. Journal of the Society of Laparoendoscopic Surgeons, 13:170-175, 2009.
  29. Lin, Z., Poritz, L.S., Franke, A., Li, T-Y, Ruether, A., Byrnes, K.A., Wang, Y., Gebhard, A.W., MacNeill, C., Thomas, N.J., Schreiber, S. and Koltun, W.A.: Genetic Association of DLG5 R30Q with Familial and Sporadic Inflammatory Bowel Disease in Men. Disease Markers, 27:193-201, 2009
  30. Poritz, L.S., Zhang, W.J., Thompson, J.L., Boyer, M., Clark, C. and Koltun, W.A.: Impaired IL-4 Induced Phosphorylation of Signal Transducer and Activator of Transcription 6 (Stat6) Null Cells From an Inflammatory Bowel Disease (IBD) Registry. Journal of Surgical Research, 162:290-298, 2009.
  31. Yu, W., Lin, Z., Kelly, A.A., Hegarty, J.P., Poritz, L.S., Wang, Y., Li, T-Y, Schreiber, S. and Koltun, W.A.: Association of a Nkx2-3 polymorphism with Crohn’s disease and expression of Nkx2-3 is up-regulated in B cell lines and intestinal tissue with Crohn’s disease. Journal of Crohn’s and Colitis, 3(3):189-195, 2009.
  32. Lin, Z., Poritz, L.S., Franke, A., Li, T-Y, Ruether, A., Byrnes, K.A., Wang, Y., Gebhard, A.W., MacNeill, C., Thomas, N.J., Schreiber, S. and Koltun, W.A.: Genetic Association of Nonsynonymous Variants of the IL23R with Familial and Sporadic Inflammatory Bowel Disease in Women. Digestive Diseases and Sciences, 55(3): 739-746, 2010.
  33. Pastor, D.M., Irby, R., Poritz, L.S.: Tumor Necrosis Factor and p53 Up-Regulated Modulator of Apoptosis Expression in Colorectal Cancer Cell Lines. Diseases of the Colon & Rectum, 53(3): 257-263, 2010.
  34. Pastor, D.M., Poritz, L.S., Olson, T.L., Kline, C.L., Harris, L.R., Koltun, W.A., Chinchilli, V.M. and Irby, R.B.: Primary Cell Lines: False Representation or Model System? A Comparison of Human Colorectal Tumors and Coordinately Established Cell Lines. International Journal of Clinical Experimental Medicine, 3(1): 69-83, 2010.
  35. Lin, Z., Nelson, L., Franke, A., Poritz, L.S., Li, T-Y, Wang, Y., MacNeill, C., Thomas, N.J., Schreiber, S. and Koltun, W.A.: OCTN1 Variant L503F is Associated with Familial and Sporadic Inflammatory Bowel Disease. Journal of Crohn’s and Colitis, 4:132-138, 2010.
  36. Yu, W., Lin, Z., Hegarty, J.P., John, G., Chen, X., Faber, P.W., Kelly, A.A., Wang, Y., Poritz, L.S., Schreiber, S. and Koltun, W.A.: Genes regulated by Nkx2-3 in siRNA- mediated knockdown B cells: Implication of endothelin-1 in inflammatory bowel disease. Molecular Genetics and Metabolism, 100(1): 88-95, 2010.
  37. Lin, Z., Hegarty, J.P., Cappel, J.A., Yu, W., Chen, X., Faber, P., Wang, Y., Kelly, A.A., Poritz, L.S., Peterson, B.Z., Schreiber, S., Fan, J.B. and Koltun, W.A.: Identification of Disease-Associated DNA Methylation in Intestinal Tissues from Patients with Inflammatory Bowel Disease. Clinical Genetics, 80(1):59-67, 2011.
  38. Mukherjee, A., McGarrity, T.J., Ruggiero, F., Koltun, W.A., McKenna, K.J., Poritz, L.S. and Baker, M.J.: The Revised Bethesda Guidelines: Extent of Utilization in a University Hospital Medical Center with a Cancer Genetics Program. Hered Cancer Clin Pract., 8(9)1- 7, 2010
  39. Sehgal, R., Berg, A., Hegarty J.P., Kelly A.A., Lin, Z., Poritz, L.S. and Koltun, W.A.: NOD2/CARD15 Mutations Correlate with Severe Pouchitis after Ileal Pouch-Anal Anastomosis. Diseases of the Colon & Rectum, 52(11):1487-94, 2010.
  40. Brown, C., Poritz, L., Stephen, W.: “Canadian Association of General Surgeons, the American College of Surgeons, the Canadian Society of Colorectal Surgeons, and the American Society of Colon and Rectal Surgeons: Evidence Based Reviews in Surgery – Colorectal Surgery”. Diseases of the Colon & Rectum, 53(4):483-485, 2011.
  41. Sehgal, R., Berg, A., Figueroa, R., Poritz, L.S., McKenna, K.J., Stewart, D.B. and Koltun, W.A.: Risk Factors for Surgical Site Infections after Colorectal Resection in Diabetic Patients. Journal American College of Surgeons, 212(1):29-34, 2011.
  42. Haveran, L.A., Sehgal, R., Poritz, L.S., McKenna, K.J., Stewart, D.B. and Koltun, W.A.: Infliximab and/or Azathioprine in the Treatment of Crohn’s Disease-Like Complications After IPAA. Diseases of the Colon & Rectum, 54(1):15-20, 2011.
  43. Poritz, L.S., Harris, L.R., Kelly, A.A. and Koltun, W.A.: Increase in the Tight Junction Protein Claudin-1 in Intestinal Inflammation. Digestive Diseases & Sciences, 56(10):2802- 2809, 2011.
  44. Lin, Z., Hegarty, J.P., Berg, A., Wang, Z., Kelly, A.A., Wang, Y., Poritz, L.S., Wu, R. And Koltun, W.A.: DLG5 P1371Q is Associated with Inflammatory Bowel Disease and Complementary to R30Q in Disease Susceptibility. Swiss Medical Weekly, 141:w13290, 2011.
  45. Poritz, L.S., Sehgal, R., Hartnett, K., Berg, A. and Koltun, W.A.: Tumor Volume and Percent Positive Lymph Nodes as a Predictor of 5-year Survival in Colorectal Cancer. Surgery, 150(4):659-55, 2011.
  46. John, G., Hegarty, J.P., Yu, W., Berg, A., Pastor, D.M., Kelly, A.A., Wang, Y., Poritz, L.S., Schreiber, S., Koltun, W.A. and Lin, Z.: NKX2-3 Variant rs11190140 is Associated with IBD and Alters Binding of NFAT. Mol. Genet. Metab., 104(1-2):174-179, 2011.
  47. Lin, Z., John, G., Hegarty, J.P., Berg, A., Yu, W., Wang, Y., Kelly, A.A., Peterson, B.Z., Poritz, L.S., Floros, J. and Koltun, W.A.: Genetic Variants and Monoallelic Expression of Surfactant Protein-D in Inflammatory Bowel Disease. Ann Hum Genet. 75(5)559-568, 2011.
  48. Yu, W., Hegarty, J.P., Berg, A., Chen, X., West, G., Kelly, A.A., Wang, Y., Poritz, L.S., Koltun, W.A. and Lin, Z.: NKX2-3 Transcriptional Regulation of Endothelin-1 and VEGF Signaling in Human Intestinal Microvascular Endothelial Cells”. PLoS One, 6(5):e20454, 2011.
  49. Lin, Z., Hegarty, J.P., Lin, T., Ostrov, B., Wang, Y., Yu, W., Kelly, A.A., Poritz, L.S. and Koltun, W.A.: Failure of Anakinra Treatment of Pyoderma Gangrenosum in an IBD Patient and Relevance to the PSTPIP1 Gene. Inflammatory Bowel Disease, 17(6):E41-2, 2011.
  50. Messaris, E., Sehgal, R., Deiling, S., Koltun, WA, Stewart, D., McKenna, K. and Poritz, LS: Dehydration is the most common indication for readmission after diverting ileostomy creation. Diseases of the Colon & Rectum, 55(2):175-180, 2012.
  51. Sehgal, R., Berg, A., Polinski, JI, Hegarty, JP, Lin, Z., McKenna, KJ, Sewart, DB, Poritz, LS and Koltun, WA: Mutations in IRGM are Associated with More Frequent Need for Surgery in Patients with Ileocolonic Crohn’s Disease. Diseases of the Colon & Rectum, 55(2):115-121, 2012.
  52. Sehgal, R., Berg, A., Polinski, J.I., Hegarty, J.P., Lin, Z., McKenna, K.J., Stewart, D.B., Poritz, L.S. and Koltun, W.A.: Genetic Risk Profiling and Gene Signature Modeling to Predict Risk of Complications after IPAA. Diseases of the Colon & Rectum, 55(3):239-48, 2012.
  53. Yu, W., Hegarty, J.P., Berg, A., Kelly, A.A., Wang, Y., Poritz, L.S., Franke, A., Schreiber, S., Koltun, W.A. and Lin, Z.: PTPN2 is Associated with Crohn’s Disease and It’s Expression is Regulated by NKX2-3. Disease Markers, 32(2):83-91, 2012.
  54. Yu, W., Lin, Z., Hegarty, J.P., Chen, X., Kelly, A.A., Wang, Y., Poritz, L.S. and Koltun, W.A.: Genes Differentially Regulated by NKX2-3 in B Cells Between Ulcerative Colitis and Crohn’s Disease Patients and Possible Involvement of EGR1. Inflammation, 35(3):889-99, 2012.
  55. Connelly TM, Sehgal R, Berg AS, Hegarty JP, Deiling S, Stewart DB, Poritz LS, Koltun WA. Mutation in TAGAP is Protective of Anal Sepsis in Ileocolic Crohn’s Disease. Diseases of the Colon & Rectum, 55(11):1145-52, 2012.
  56. Rotramel, A., Berg, A., Poritz, L.S., Messaris, E., Berg, A. and Stewart D.: PPI Therapy and Albumin are Better Predictors of Recurrent Clostridium Difficile Colitis than Choice of Antibiotics. Journal of Gastrointestinal Surgery, 16(12):2267-2273, 2012.
  57. Poritz, L.S., Sehgal, R., Berg, A.S., Laufenberg, L., Choi, C. and Williams, E.D.: Chronic Use of PPI and H2 Antagonists Decreases the Risk of Pouchitis After IPAA for Ulcerative Colitis. Journal of Gastrointestinal Surgery, 17(6):1027-1031, 2013.
  58. Connelly, T.M., Berg, A.S., Hegarty, J.P., Brinton, D., Deiling, S., Poritz, L.S., Koltun, W.A. and Stewart, D.B.: Single Nucleotide Polymorphism in the STAT5 Gene Favors Colonic as Opposed to Small Bowel Inflammation in Crohn’s Disease. Diseases of the Colon and Rectum, 56(9):1068-1074, 2013.
  59. Kline CL, Schiccitano A, Zhu J, Beachler C, Sheikh H, Harvey HA, Mackley HB, McKenna K, Staveley-O’Carroll K, Poritz L, Messaris E, Stewart D, Sivik J, El-Deiry WA. Personalized dosing via pharmacokinetic monitoring of 5-Fluorouracil might reduce toxicity in early- or late-stage colorectal cancer patients treated with infusional 5-Fluorouracil-based chemotherapy regimens. Clinical Colorectal Cancer, 13(2):119-126, 2014.
  60. Salgado, J., Messaris, E., Deiling, S., Connelly, T.M., Berg, A.S., Stewart, D.B., McKenna, K., Poritz, L.S. and Koltun, W.A.: Increased Risk of Incisional Hernia After Sigmoid Colectomy for Diverticulitis Compared to Colon Cancer. JACS, 218(5):920-928, 2014.
  61. Connelly, T.M., Berg, A., Hegarty, J.P., Harris, L., Brinton, D., Deiling, S., Poritz, L.S. and Koltun, W.A.: The TNFSF15 Gene Single Nucleotide Polymorphism rs7848647 Is Associated with Surgical Diverticulitis. Annals of Surgery, 259(6):1132-1137, 2014.

NON-PEER REVIEWED ARTICLES

  1. Poritz, L.S. and Koltun, W.A.: Techniques of Disease Activity Assessment in Crohn’s Disease. Seminars in Colon and Rectal Surgery., 12(1):16-21, 2001.
  2. Poritz, L.S.: Anal Fissure. eMedicine.
  3. Poritz, L.S.: Rectal Prolapse. eMedicine.
  4. Poritz, L.S.: Perineal Procedures for Prolapse. Operative Techniques in General Surgery, 7(3):121-125, 2005.
  5. Poritz, L.S.: Research in Academic Colon and Rectal Surgery: Keys to Success. Clinics in Colon and Rectal Surgery, 19:148-155, 2006.
  6. Poritz, L.S.: Consequences of the Retained Rectum in Inflammatory Bowel Disease. Seminars in Colon & Rectal Surgery, June 2006.
  7. Poritz, L.S.: Alteration of the Tight Junction Complex in Intestinal Inflammation Career Development Award #001. Seminars in Colon and Rectal Surgery, 17(4):199-205, 2006.
  8. Poritz, L.S.: Altemeier Using the Circular Stapler. Operative Techniques in General Surgery, 10(4), 194-197, 2008.
  9. Brown, C., Poritz, L., Stephen, W.: Canadian Association of General Surgeons, the American College of Surgeons, the Canadian Society of Colorectal Surgeons, and the American Society of Colon and Rectal Surgeons: Evidence Based Reviews in Surgery – Colorectal Surgery. Diseases of the Colon & Rectum, 53(4):483-485, 2010.

BOOK CHAPTERS

  1. Koltun, W.A., and Poritz, L.S.: Appendix. In Breckler, G.L., Maull, K., (Ed.), General Surgery Pearls of Wisdom, Boston Medical Publishing Corporation, 1998.
  2. Koltun, W.A., and Poritz, L.S.: Appendix. In Breckler, G.L., Maull, K., (Ed.), General Surgery Medical Student Pearls of Wisdom, USMLE Parts II & III Board Review, Boston Medical Publishing Corporation, 1998.
  3. Koltun, W.A. and Poritz, L.S.: Surgical Therapy for Inflammatory Bowel Disease, In The Clinicians Guide to Inflammatory Bowel Disease, Chapter 12, pp 199-219, 2003. Poritz, L.S.: IBD: Management of Symptomatic Anal Fistulas in Patients with Crohn’s Disease, in Difficult Decisions in Colorectal Surgery – An Evidence Based Approach, in press, 2016.

Grants (Selected):

Competitive Peer-Reviewed Grant Support:

Danielle Pastor, D.O. (PI) 07/01/08 – 06/30/09
Lisa S. Poritz, M.D. (Mentor)
ASCRS Resident Research Award - $20,000
“ The Effect of Inflammatory Mediators on Colorectal Cancer Tumor Suppressor and Protooncogene Expression”

Danielle Pastor, D.O. (PI) 07/1/2009 – 06/30/2010
Lisa S. Poritz, M.D. (Mentor)
ASCRS Resident Research Award - $20,000
“Tumor Necrosis Factor Regulated Apoptosis and Metastasis in Colorectal Cancer”

Lisa S. Poritz, M.D. (Principal Investigator) 09/17/07 – 08/31/12
NIH (K08) - $124,146 (1st year)
$620,730 (Full 5 years)
#5K08GM081595
“Alteration of the Tight Junction Complex in Pouchitis”

Lisa S. Poritz, M.D. 12/31/01 – 12/31/03
Career Development Award – American Society of Colon and Rectal Surgeons $80,000 (2 year)
“Tight Junction Structure and Function in Intestinal Inflammation”

Lisa S. Poritz, M.D. 7/1/96 – 6/30/97
Leon Hirsch Fellowship Award, American Society of Colon and Rectal Surgeons

Grants and Contracts from Industry:

Lisa S. Poritz, M.D. (sub-investigator) 08/23/02 – 08/23/05
Merck Prevent
“A Prospective, Multicenter, Double-Blind, Randomized, Comparative Study to Evaluate the
Safety, Tolerability, and Efficacy of a Single Dose of XXXX Versus Cefotetan for the
Prophylaxis of Surgical Site Infection Following Elective Colorectal Surgery”

Lisa S. Poritz, M.D. (sub-investigator) 07/01/02 – 12/31/05
North American Surgical Crohn’s
“A Multi-Centre Randomized Controlled Trial to Compare Stapled Functional End-to-End
Anastomosis with Sutured End-to-End Anastomosis Following Resection for Primary or
Recurrent Ileocolonic Crohn’s Disease"

Lisa S. Poritz, M.D. (Principal Investigator) 08/12/03 – 08/11/06
Duke Clinical Research Institute - American College of Surgeons Oncology Group - $15,000
“A Prospective Study of the Prognostic Significance of Microsatellite Instability in Patients with Early Age-of-Onset Colorectal"

Lisa S. Poritz, M.D. (Principal Investigator) 10/15/05 –
Duke Clinical Research Institute – American College of Surgeons Oncology Group - $15,000
“A Phase II Trial of Neoadjuvant Chemoradiation and Local Excision for uT2uN0 Rectal Cancer”

INVITED PROFESSORSHIPS AND LECTURES

International:

  1. “Intestinal LFA-1 Expression In The Rat With Graft-Versus-Host Disease After Small
    Bowel Transplantation”
    University of Toronto
    Colorectal Rounds
    December 2, 1999
  2. "Structure of Limited Project and Career Development Awards”
    2011 Annual Scientific Meeting
    The American Society of Colon and Rectal Surgeons
    Vancouver Convention Center
    Vancouver, Canada
    May 15, 2011

National:

  1. “Cytomegalovirus (CMV): A Surgical Disease?”
    Page, M.J., Dreese, J.A., Poritz, L.S., Koltun, W.A
    8th Annual Winter Meeting: Midwest Society of Colon and Rectal Surgeons
    Steamboat, CO
    March 11, 1999
  2. “Extended Follow-up of Patients Treated with Cytotoxic Chemotherapy (CCT) for Intraabdominal Desmoid Tumors (DTs).”
    Poritz, L.S., Blackstein, M., Berk, T., Gallinger, S., McLeod, R., Cohen, Z.
    Northeast Society of Colon and Rectal Surgeons
    West Palm Beach, Florida
    November 14, 2000
  3. “Imuran/Flagyl/Remicade…Is the Latest Silver Bullet a Blank?”
    SSAT/ASCRS Joint Symposium
    Digestive Disease Week
    San Francisco, California
    May 20, 2002
  4. “Is the Colon Worth Saving?”
    Mayo Clinic
    Rochester, Minnesota
    May 7, 2003
  5. “FAP: IRA vs Pouches, Stapled IPAA vs Mucosectomy”
    Meet the Professor Breakfast
    American Society of Colon and Rectal Surgeons Meeting
    New Orleans, Louisiana
    June 23, 2003
  6. “Adjuvant Treatment of Colorectal Cancer”
    Core Subject Update
    American Society of Colon and Rectal Surgeons Meeting
    Dallas, Texas
    May 8, 2004
  7. “How Should Complex Crohn’s Disease Be Treated in the Remicade Era?”
    SSAT/ASCRS Joint Symposium
    Digestive Disease Week
    Chicago, Illinois
    May 17, 2005
  8. “Funding/Facilitating the “Start-Up” Effort”
    American Society of Colon and Rectal Surgeons Meeting
    St. Louis, MO
    June 2, 2007
  9. “The Leading Edge – Update on the Latest in Research and Development”
    American Society of Colon and Rectal Surgeons Meeting
    Hollywood, FL
    May 3, 2009
  10. “Basic Science Research – How to Get Started?”
    Meet the Professor Breakfast
    American Society of Colon and Rectal Surgeons Meeting
    Hollywood, FL
    May 5, 2009
  11. “Bowel Preps – Yes or No?”
    Meet the Professor Breakfast
    American Society of Colon & Rectal Surgeons Meeting
    Minneapolis, MN
    May 17, 2010
  12. “Crohn’s Colitis: Is Ileostomy the Best Answer?”
    Inflammatory Bowel Disease Update
    American College of Surgeons 96th Annual Meeting
    Washington, DC
    October 7, 2010
  13. “Addressing the Young Surgeon’s Concerns”
    Young Surgeons Luncheon Symposium
    American Society of Colon and Rectal Surgeons Meeting
    Vancouver, BC, Canada
    May 15, 2011
  14. “Pouchitis and Other Pouch Problems”
    Meet the Professor Breakfast
    American Society of Colon and Rectal Surgeons Meeting
    San Antonio, TX
    June 6, 2012
  15. “Surgical Management of IBD in the Age of Biologics”
    ACG Regional Postgraduate Course
    LGS Annual Meeting
    New Orleans, LA
    March 7, 2014
  16. “Alteration of the Tight Junction Complex in Intestinal Inflammation”
    Department of Surgery Research Day
    Baylor Scott and White
    Guest Speaker
    Round Rock, TX
    May 1, 2015

Regional (Selected):

  • “Theories on the Causes of IBD”
    • Inflammatory Bowel Disease, A Patient Symposium
    • The Pennsylvania State University
    • The Milton S. Hershey Medical Center
    • Hershey, Pennsylvania
    • November 4, 2000
  • “Perianal Crohn’s Disease”
    • Wilkes Barre – GUT Club
    • Wilkes Barre, Pennsylvania
    • April 24, 2001
  • “Not All Rectal Bleeding and Pain is Hemorrhoids”
    • Keypro
    • Harrisburg, Pennsylvania
    • May 9, 2001
  • “Management of Perineal Complications of Crohn’s Disease”
    • Waynesboro Hospital CME Program
    • Waynesboro, Pennsylvania
    • October 19, 2001
  • “Surgery For Crohn’s Disease in the Era of Remicade”
    • Advances in Immunology Speakers Program
    • Harrisburg, Pennsylvania
    • October 23, 2001
  • “Colonoscopy and Colon Cancer”
    • Bayer Consumer Care
    • Myerstown, Pennsylvania
    • January 21 and 29, 2002
  • “What’s New in the Search for the Cause of IBD”
    • Inflammatory Bowel Disease, A Patient Symposium
    • The Pennsylvania State University
    • The Milton S. Hershey Medical Center
    • Hershey, Pennsylvania
    • April 20, 2002
  • “Is the Colon Worth Saving?”
    • GUT Club
    • Lewisburg, Pennsylvania
    • April 29, 2003
  • “Laparoscopy and Other Advances in the Surgery for Colon Cancer”
    • Colorectal Cancer Symposium
    • The Pennsylvania State University
    • The Milton S. Hershey Medical Center
    • Hershey, Pennsylvania
    • March 19, 2005
  • “A Decade of IBD Research”
    • Clinical/Research Grand Rounds
    • The Pennsylvania State University
    • The Milton S. Hershey Medical Center
    • Hershey, Pennsylvania
    • March 15, 2007
  • “Surgery for Hereditary Colon Cancer”
    • Colorectal Cancer Symposium – Advances in the Management of Colorectal Cancer
    • Hershey Lodge
    • Hershey, PA
    • March 15, 2008
  • “Alteration of the Tight Junction Complex in Intestinal Inflammation”
    • Research Grand Rounds
    • The Pennsylvania State University
    • The Milton S. Hershey Medical Center
    • Hershey, Pennsylvania
    • February 11, 2010
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